Tramadol with acetaminophen (2024)

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Tramadol with acetaminophen

Drug Class: Analgesics (Atypical opioid)
Brand Names: : Ultracet

Dosages

In a combination pill, 75 mg tramadol and 650 mg acetaminophen every 4 to 6 hours as needed.

Potential Side Effects

Constipation; diarrhea; dizziness; drowsiness; lightheadedness; loss of appetite; mental confusion; nausea; shortness of breath; urinary retention; vomiting.

Special Instructions

Do not increase the dose on your own or stop treatment abruptly unless told to do so by a doctor. Do not drive, operate machinery or perform other potentially dangerous activities until you know whether the medication will affect your ability to do them safely.

Be Aware

This medicine contains acetaminophen. Do not use with any other products containing acetaminophen. Too much acetaminophen can cause serious liver damage or death. Limit the amount of acetaminophen you take to 3000 mg/day unless otherwise directed by your doctor. Drinking alcohol increases your risk of liver damage. Tell your doctor if you have a history of liver disease or alcohol or drug abuse, or if you have three or more alcoholic drinks daily. Also tell your doctor if you take the blood-thinning drug warfarin (Coumadin). Acetaminophen prolongs the time that drug is active in your body, increasing bleeding risk. Your doctor may need to adjust your dosage. Rarely, acetaminophen may cause serious skin reactions, including Stevens-Johnson syndrome, which can be deadly. Stop taking acetaminophen and call your doctor if you develop a skin rash.

Opioids can slow breathing and suppress the cough reflex. Before taking an opioid, tell your doctor if you have a history of lung disease or breathing difficulties. Taking opioids with certain other drugs can increase the risk of dangerous side effects. Especially tell your doctor if you take antihistamines (allergy medications), tranquilizers, sleeping pills, muscle relaxants or other pain medication, or if you have a history of alcohol or drug abuse.

Seizures have been associated with the use of tramadol. Taking this drug with certain antidepressants or with other opioids may increase this risk.

LAST UPDATED: 03/27/2014

TheArthritis TodayDrug Guide is meant for education – not self-medicating. Arthritis Today, the Arthritis Foundation and the Drug GuideMedical Review Paneldo not endorse any products mentioned in this guide. While we endeavor to keep the information up to date, we make no representations or warranties about the completeness of the information provided.

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Tramadol with acetaminophen (2024)

FAQs

Tramadol with acetaminophen? ›

Descriptions. Tramadol and acetaminophen combination is used to relieve acute pain severe enough to require an opioid treatment and when other pain medicines did not work well enough or cannot be tolerated. When used together, the combination provides better pain relief than either medicine used alone.

What should you not mix with tramadol? ›

Do not take medicines called monoamine oxidase inhibitors or MAOIs (which are used to treat depression) with tramadol. The combination can cause significant side effects such as anxiety, confusion and hallucinations.

Can you take 2 Tylenol PM with tramadol? ›

diphenhydrAMINE traMADol

Using traMADol together with diphenhydrAMINE may increase the risk and/or severity of some side effects such as dizziness, drowsiness, confusion, difficulty concentrating, difficulty urinating, dry mouth, abdominal cramping, and constipation.

Is tramadol stronger than hydrocodone with acetaminophen? ›

The Drug Enforcement Administration (DEA) classifies tramadol as a Schedule IV drug and hydrocodone as a Schedule II drug. This means tramadol is considered less potent than hydrocodone.

What is better for pain tramadol or Tylenol with codeine? ›

Official answer. Both tramadol and codeine are prescription painkillers, and they seem to be equally effective in terms of pain relief. There is no evidence that tramadol is any stronger than codeine at relieving pain. Codeine is an opiate medicine and tramadol is a synthetic (man-made) opioid.

Why can't you take Tylenol with tramadol? ›

The combination of tramadol and acetaminophen may increase the risk of serotonin syndrome. This risk is possible if you have certain medical problems or are taking certain medications. Symptoms of serotonin syndrome may include: agitation.

What pain reliever can I take with tramadol? ›

Yes, tramadol can typically be taken with nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn). In fact, taking NSAIDs with opioids like tramadol can be an effective way to relieve pain in some situations.

How long does it take for a tramadol to kick in? ›

You will feel less pain around 30 to 60 minutes after taking standard tramadol. The pain relief wears off after 4 to 6 hours. Slow-release tramadol tablets and capsules can take a day or two to start working but the pain relief will last for longer.

Can I take 2 tramadol 50mg at once? ›

Take tramadol hydrochloride tablets exactly as prescribed by your healthcare provider. Use the lowest dose possible for the shortest time needed. Take your prescribed dose as indicated by your healthcare provider. The maximum dosage is 1 or 2 tablets every 4 to 6 hours, as needed for pain relief.

What pain pill is better than tramadol? ›

Oxycodone and tramadol are two prescription opioid medications used to help relieve pain. Even though these medications have a similar use, oxycodone is known to be more potent, with stronger pain-relieving capabilities than tramadol.

Is tramadol stronger than gabapentin? ›

This also means that gabapentin has a depressing or sedative effect on the brain. Although it's not as potent as tramadol, gabapentin is addictive.

What is the strongest pain relief? ›

Morphine is a stronger opioid drug. Other examples of strong opioids include diamorphine, oxycodone, fentanyl, methadone and buprenorphine. Opioid medicines come in many forms including tablets, capsules, liquids, skin patches and injections.

Is percocet stronger than tramadol? ›

Percocet is a combination drug that includes oxycodone and acetaminophen. Because oxycodone is a much more potent drug than tramadol, you should not take them together unless instructed to do so by your doctor.

What foods should you avoid when taking tramadol? ›

Do not drink any alcohol as this will make you feel more tired. Stick to simple meals and do not eat rich or spicy food. It might help to take your tramadol after you've eaten a meal or snack. If you're being sick, try small frequent sips of water.

What supplements should not be taken with tramadol? ›

5-HTP and L-tryptophan are converted to serotonin in the brain. While no interactions have yet been reported with tramadol and 5-HTP or L-tryptophan, taking 5-HTP or L-tryptophan with tramadol may increase the risk of tramadol-induced side effects, including serotonin syndrome.

What is the best combination with tramadol? ›

Combining tramadol and paracetamol

Paracetamol is often used with stronger pain medicine (analgesics) such as tramadol. This gives extra pain relief when required. Taking paracetamol regularly with tramadol gives you best pain relieving effect. Your dose of tramadol can be stepped up and down depending on your pain.

When should tramadol be avoided? ›

Who can and cannot take tramadol
  1. ever had an allergic reaction to tramadol or any other medicine.
  2. a condition which causes seizures or fits.
  3. a head injury.
  4. an addiction to alcohol, strong painkillers or recreational drugs.
  5. breathing difficulties.
  6. kidney or liver problems.
  7. ever had a reaction to other strong painkillers.

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